Delphi consensus recommendations for a treatment algorithm in pulmonary sarcoidosis

zu Verbundenen Objekten

Abstract: Pulmonary sarcoidosis presents substantial management challenges, with limited evidence on effective therapies and phenotypes. In the absence of definitive evidence, expert consensus can supply clinically useful guidance in medicine. An international panel of 26 experts participated in a Delphi process to identify consensus on pharmacological management in sarcoidosis with the development of preliminary recommendations.

The modified Delphi process used three rounds. The first round focused on qualitative data collection with open-ended questions to ensure comprehensive inclusion of expert concepts. Rounds 2 and 3 applied quantitative assessments using an 11-point Likert scale to identify consensus.

Key consensus points included glucocorticoids as initial therapy for most patients, with non-biologics (immunomodulators), usually methotrexate, considered in severe or extrapulmonary disease requiring prolonged treatment, or as a steroid-sparing intervention in cases with high risk of steroid toxicity. Biologic therapies might be considered as additive therapy if non-biologics are insufficiently effective or are not tolerated with initial biologic therapy, usually with a tumour necrosis factor-α inhibitor, typically infliximab.

The Delphi methodology provided a platform to gain potentially valuable insight and interim guidance while awaiting evidenced-based contributions

Sprache
Englisch
Umfang
Online-Ressource
Anmerkungen
European respiratory review. - 29, 155 (2020) , 190146, ISSN: 1600-0617
Standort
Deutsche Nationalbibliothek Frankfurt am Main

Urheber
Rahaghi, Franck F.
Baughman, Robert P.
Saketkoo, Lesley Ann
Sweiss, Nadera J.
Barney, Joseph B.
Birring, Surinder S.
Costabel, Ulrich
Crouser, Elliott D.
Drent, Marjolein
Gerke, Alicia K.
Grutters, Jan C.
Hamzeh, Nabeel Y.
Huizar, Isham
James, Walter Ennis
Kalra, Sanjay
Kullberg, Susanna
Li, Huiping
Lower, Elyse E.
Maier, Lisa A.
Mirsaeidi, Mehdi
Müller-Quernheim, Joachim
Carmona Porquera, Eva M.
Samavati, Lobelia
Valeyre, Dominique
Scholand, Mary Beth
Ereignis
Veröffentlichung
(wo)
Freiburg
(wer)
Universität
(wann)
2020

DOI
10.1183/16000617.0146-2019
URN
urn:nbn:de:bsz:25-freidok-1661574
Rechteinformation
Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
25.03.2025, 13:41 MEZ

Datenpartner

Dieses Objekt wird bereitgestellt von:
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Original beim Datenpartner anzeigen

Beteiligte

  • Rahaghi, Franck F.
  • Baughman, Robert P.
  • Saketkoo, Lesley Ann
  • Sweiss, Nadera J.
  • Barney, Joseph B.
  • Birring, Surinder S.
  • Costabel, Ulrich
  • Crouser, Elliott D.
  • Drent, Marjolein
  • Gerke, Alicia K.
  • Grutters, Jan C.
  • Hamzeh, Nabeel Y.
  • Huizar, Isham
  • James, Walter Ennis
  • Kalra, Sanjay
  • Kullberg, Susanna
  • Li, Huiping
  • Lower, Elyse E.
  • Maier, Lisa A.
  • Mirsaeidi, Mehdi
  • Müller-Quernheim, Joachim
  • Carmona Porquera, Eva M.
  • Samavati, Lobelia
  • Valeyre, Dominique
  • Scholand, Mary Beth
  • Universität

Entstanden

  • 2020

Ähnliche Objekte (12)

A Delphi consensus statement for digital surgery

A Delphi consensus statement for digital surgery

Using Delphi technique to build consensus in practice

Artikel

Using Delphi technique to build consensus in practice

Organ donation organization architecture: recommendations from an international consensus forum

Organ donation organization architecture: recommendations from an international consensus forum

Providing actionable recommendations : a movie recommendation algorithm with explanation capability

Hochschulschrift

Providing actionable recommendations : a movie recommendation algorithm with explanation capability

Detection and characterization of colorectal polyps using high-definition white light and i-Scan: Evidence-based consensus recommendations using a modified Delphi process

Detection and characterization of colorectal polyps using high-definition white light and i-Scan: Evidence-based consensus recommendations using a modified Delphi process

Delphi : A Democratic and Cost-Effective Method of Consensus Generation in Transplantation

Delphi : A Democratic and Cost-Effective Method of Consensus Generation in Transplantation

Consensus‐Based Technical Recommendations for Clinical Translation of Renal Phase Contrast MRI

Consensus‐Based Technical Recommendations for Clinical Translation of Renal Phase Contrast MRI

Consensus Recommendations of the German Consortium for Hereditary Breast and Ovarian Cancer

Consensus Recommendations of the German Consortium for Hereditary Breast and Ovarian Cancer

Recommendations for evidence based endoscopic surgery : [the updated EAES consensus development conferences]

Recommendations for evidence based endoscopic surgery : [the updated EAES consensus development conferences]

Global consensus recommendations on improving the safety of chronic total occlusion interventions

Global consensus recommendations on improving the safety of chronic total occlusion interventions

Delphi studies in social and health sciences- recommendations for an interdisciplinary standardized reporting (DELPHISTAR) : : results of a Delphi study

Delphi studies in social and health sciences- recommendations for an interdisciplinary standardized reporting (DELPHISTAR) : : results of a Delphi study

Indicators of outcome quality in peripheral arterial disease revascularisations : : a Delphi expert consensus

Indicators of outcome quality in peripheral arterial disease revascularisations : : a Delphi expert consensus

Verbundene Objekte